Ayurveda concepts of nephrotic syndrome in pediatrics

Abstract

Sabir Ali*, Renu Rathi, Monika Meshram, Hemant Nikum and Dhiraj Khobragde

Nephrotic syndrome is a serious chronic kidney disease that affects a large number of children. The autoimmune condition nephrotic syndrome has evolved. T lymphocyte dysregulation and vascular permeability variables have been found to contribute to changes in podocyte function and permselectivity that result in NS, according to pathogenesis studies. Treatment outcome is determined by steroid response. The majority of them are intitally susceptible but later recover or become steroid reliant or resistant. Treatments such as levamisole, cyclophosphamide, cyclosporine, long-acting alternative cortiosteroids, and others have been used in combination with different protocols to treat steroid-dependent or resistant NS, with varying effectiveness or greater adverse effects. As a result, an alternative therapy is required. polyherbal formulations with an immunomodulator, nephroprotective, and antioxidant activities may be more effective as a supplement to contemporary therapeutic medications in the treatment of steroid-dependent or resistant instances of NS.