TUBEROUS SCLEROSIS WITH BILATERAL RENAL CELL CARCINOMA IN A CHILD: A CASE REPORT

Abstract

Sanjay Choudhuri, Jeevanjyoti Mishra, Gyan Prakash Singh, Datteswar Hota

Tuberous sclerosis complex (TCS) is an autosomal dominant disease which comes under a group of diseases known as neurocutaneous syndrome. Incidence of TCS is around 1 in 6000. The clinical triad of papular facial nevus, seizures and mental retardation is found in less than 50% of the patients. Renal lesions in TCS commonly consist of simple renal cyst and angiomyolipomas. Renal cell carcinoma though rarely associated with tuberous sclerosis may be its significant manifestations. We report a case of TCS with bilateral renal cell carcinoma in a 12 year old child with classical radiological and clinical signs. <